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pentobarbital will boost the degree or effect of ivosidenib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of ivosidenib with potent CYP3A4 inducers reduced ivosidenib plasma concentrations.pentobarbital will minimize the extent or impact of capivasertib by impacting hepatic/intestin